ODCs

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1 OMIM reference -
1 associated gene
No signs/symptoms info

PROTEIN INTERACTIONS: 1

2 OMIM references -
1 associated gene
10 signs/symptoms

Pelizaeus-Merzbacher-like due to HSPD1 mutation

Fibronectin glomerulopathy


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	HSPD1	(0.63)	FN1

Citations in the biomedical literature:

Pelizaeus-Merzbacher-like due to HSPD1 mutation		Fibronectin glomerulopathy
	Synonym(s): - Mitochondrial HSP60 chaperonopathy		Synonym(s): - GFND - Glomerulopathy with fibronectin deposits

	Classification (Orphanet): - Rare genetic disease - Rare neurologic disease		Classification (Orphanet): - Rare genetic disease - Rare renal disease

	Classification (ICD10): - Endocrine, nutritional and metabolic diseases -		Classification (ICD10): - Diseases of the genitourinary system -

	Epidemiological data: Class of prevalence: unknown Average age onset: neonatal/infancy Average age of death: before age 5 Type of inheritance: autosomal recessive		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: variable Average age of death: - Type of inheritance: autosomal dominant

	External references: 1 OMIM reference - No MeSH references		External references: 2 OMIM references - No MeSH references

Fibronectin glomerulopathy
	Very frequent - Autosomal dominant inheritance - Chronic arterial hypertension - Edema of the legs / lower limbs - Functional anomalies of the kidney and the urinary tract - Hematuria / microhematuria - Nephrotic syndrome - Proteinuria - Renal failure - Renal glomerular defect / glomerulopathy Occasional - Intracranial / cerebral / meningeal hemorrhage
Pelizaeus-Merzbacher-like due to HSPD1 mutation
(no data available)